• Gastrointestinal
Name No. Patient Profile Purpose
MK3475-811 (KEYNOTE 811) 18-12

Cancer of the oesophagus or gastro-oesophageal junction which has spread (metastasised).

To compare survival between the two groups – those treated with Trastuzumab, chemotherapy and Pembrolizumab and those treated with Trastuzumab, chemotherapy and placebo.


  • Gastrointestinal
Name No. Patient Profile Purpose
COLLOSUS 17-26

Patients with cancer of the colon or rectum which has spread (metastasised).

To find and test new stratification tools (ways of dividing patients into different groups) in patients who have microsatellite stable RAS mutant metastatic colorectal cancer.


  • Gastrointestinal
Name No. Patient Profile Purpose
ARMO Artist 16-77

Patients with cancer of the pancreas which has spread (metastasised)

This trial aims to compare the effectiveness of a drug called AM0010 in combination with FOLFOX with FOLFOX alone.


  • Gastrointestinal
Name No. Patient Profile Purpose
MErCuRIC1 16-58

RAS mutant and RAS wild type (with aberrant c-MET) Colorectal Cancer.

This trial is designed to try two new cancer drugs together for the first time, Binimetinib and PF-02341066/Crizotinib for treatment of colorectal cancer.


  • Gastrointestinal
Name No. Patient Profile Purpose
BMS CA209-577 16-73

Cancer of the oesophagus, or the junction between the oesophagus and the stomach.

The purpose of this trials is to determine the effectiveness of the drug nivolumab in patients with residual disease after CRT and surgery.


  • Gastrointestinal
Name No. Patient Profile Purpose
STRATEGIC-1 14-20

Cancer of the colon or rectum.

The purpose of this trial is to compare two standard chemotherapy treatment strategies.


  • Gastrointestinal
Name No. Patient Profile Purpose
BMS CA209-142 14-19

Cancer of the colon.

The purpose of this trial is to examine the effectiveness of the drug Nivolumab in combination with other drugs.


  • Gastrointestinal
Name No. Patient Profile Purpose
TRI-LARC 12-38

Cancer of the rectum.

The purpose of this trial is to compare two radiotherapy techniques for treating locally advanced rectal cancer.


  • Gastrointestinal
Name No. Patient Profile Purpose
PDAC Plasma Biomarker 12-31

Pancreatic cancer

The purpose of this trial is to investigate how proteins and genes respond to pancreatic cancer treatment.


  • Gastrointestinal
Name No. Patient Profile Purpose
CRAC Plasma Biomarker 12-27

Colorectal cancer (colon or rectal)

The purpose of this trial is to investigate what proteins and genes are related to the recurrence of colorectal cancer.