About this trial

This trial is to compare the use of Chemoradiotherapy with or without Pembrolizumab for the treatment of High-risk Locally Advanced Cervical Cancer

Patient Profile

For women over 18 with Stage IB2-IIB and Stage III-IV A cervical cancer.

Where’s this trial being run?

Cork University Hospital and St James’s Hospital

Can I join this study / trial?

The first thing you do is to talk to your doctor and/or the cancer trials research team in your hospital. The contact details for the cancer trials research units in Ireland is here.

Why not Print this page and bring it with you. It will help your doctor and research team advise you.

For more detailed information


Here’s a list of questions you may have for your doctor or local cancer research team.

Summary Data

Name: KEYNOTE-A18 / ENGOT-cx11
Number: 21-03
Full Title:

A Randomized, Phase 3, Double-Blind Study of Chemoradiotherapy With or
Without Pembrolizumab for the Treatment of High-risk, Locally Advanced Cervical Cancer

Principal Investigator: Dr Dearbhaile Collins
Type: Collaborative

Merck Sharp & Dohme

Recruitment Started: Global: 12 May 2020
Ireland: Feb 2021
Global Recruitment Target: 980
Ireland Recruitment Target: N/A