About this trial

Interventional, randomised, Phase 3 study

Patient Profile

previously treated metastatic NSCLC with a KRAS G12C mutation.

Where’s this trial being run?

Beaumont Hospital, St James’s Hospital, Tallaght University Hospital, St Vincents University Hospital, University Hospital Limerick, and University Hospital Galway

Can I join this study / trial?

The first thing you do is to talk to your doctor and/or the cancer trials research team in your hospital. The contact details for the cancer trials research units in Ireland is here.

Why not Print this page and bring it with you. It will help your doctor and research team advise you.

For more detailed information


Here’s a list of questions you may have for your doctor or local cancer research team.

Summary Data

Name: KRYSTAL-12
Number: 21-13
Full Title:

A Randomized Phase 3 Study of MRTX849 Versus Docetaxel in Patients With Previously Treated Non-Small Cell Lung Cancer With KRAS G12C Mutation

Principal Investigator: Dr Jarushka Naidoo
Type: Industry Sponsored

Mirati Therapeutics Inc.

Recruitment Started: Global: January 2021
Ireland: Yes
Global Recruitment Target: 340
Ireland Recruitment Target: 9