About this trial

MK-7684A is an experimental treatment. It is an immunotherapy. This means it works by stimulating the body’s own immune system to fight the cancer. It is a combination of 2 drugs: MK 7684 and pembrolizumab (pembro).
MK-7684 is an experimental drug. It is also called vibostolimab. It has not been approved for sale.
Pembro has been approved by certain health authorities for treating various cancers.
Atezolizumab is also an immunotherapy. It has been approved by certain health authorities for treating various cancers, including SCLC.

Patient Profile

This study is for patients with Newly Diagnosed Extensive-Stage Small Cell Lung Cancer Who meet the following criteria:
– ECOG Performance status of 0-1 (this is a scale measuring your ability to carry out normal activities including your ability to care for yourself, daily and physical activities)
– No active brain metastases requiring treatment
– No autoimmune or neurologic paraneoplastic syndromes
– No pneumonitis or interstitial lung disease

Where’s this trial being run?

Beaumont Hospital and St James’s Hospital

Can I join this study / trial?

The first thing you do is to talk to your doctor and/or the cancer trials research team in your hospital. The contact details for the cancer trials research units in Ireland is here.

Why not Print this page and bring it with you. It will help your doctor and research team advise you.

For more detailed information


Here’s a list of questions you may have for your doctor or local cancer research team.

Summary Data

Name: MK7684A-008
Number: 22-06
Full Title:

Phase III Study of MK-7684A with
Platinum-based Chemotherapy 1L Extensive Stage SCLC

Principal Investigator: Dr Dearbhaile Collins
Type: Industry Sponsored


Recruitment Started: Global: Yes
Ireland: Yes
Global Recruitment Target: 450
Ireland Recruitment Target: 6+