Questions about cancer? Freephone 1800 200 700 Irish Cancer Society Nurseline

About this trial

The purpose of this trial investigates the levels of hormones in a patient’s blood, which may predict the likelihood of future infertility both during the period of chemotherapy and for some time after completion of chemotherapy.

There is growing evidence that the type of chemotherapy administered influences ovarian reserve after the end of chemotherapy. This is the first study to test if certain hormone levels give an accurate estimation during the chemotherapy as to whether a patient will become infertile in the future.

Patient Profile

Premenopausal breast cancer patients (up to 50 years of age) who are to receive chemotherapy.

Blood samples will be collected before, during and after chemotherapy – 11 timepoints in total over a 3 year period. There is also an option of completing 2 short questionnaires about general health.

Where’s this trial being run?

Beacon Hospital, Beaumont Hospital, Bon Secours Cork, Cork University Hospital, Sligo University Hospital, St James’s Hospital, Tallaght University Hospital, St Vincents University Hospital, and University Hospital Waterford

Can I join this study / trial?

The first thing you do is to talk to your doctor and/or the cancer trials research team in your hospital. The contact details for the cancer trials research units in Ireland is here.

Why not Print this page and bring it with you. It will help your doctor and research team advise you.

For more detailed information


Here’s a list of questions you may have for your doctor or local cancer research team.

Summary Data

Name: Ovarian Reserve
Number: 10-16
Full Title:

A study to determine alteration of hormone levels in premenopausal patients receiving adjuvant or neo-adjuvant chemotherapy for breast cancer.

Principal Investigator: Dr Janice Walshe (St Vincent's University Hospital) and Prof Bryan Hennessy (Beaumont Hospital)
Type: In-House

Cancer Trials Ireland

Recruitment Started: Global: Not Applicable
Ireland: October 2012 ( Recruitment on hold)
Global Recruitment Target: Not Applicable
Ireland Recruitment Target: 250