All of the following trials are conducted at Our Lady’s Children’s Hospital, Crumlin.

Name No. Type Date Opened Principal Investigator(s) Title No. on this trial
JMML-Mesrat Study 16-51 Collaborative June 2015 Dr. Owen Smith

DNA methylation signatures and response to the azacitidine therapy in juvenile myleomonocytic leukaemia (JMML) Classification of Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) – AALL08B1

Crumlin Children’s Hospital (1)
Name No. Type Date Opened Principal Investigator(s) Title No. on this trial
Interfant 06 16-53 Collaborative November 2014 Dr Owen Smith

International collaborative treatment protocol for Infants under one year with Acute Lymphoblastic or Biphenotypic Leukemia.

Crumlin's Children Hospital (4)
Name No. Type Date Opened Principal Investigator(s) Title No. on this trial
EURO-Ewing 2012 16-52 Collaborative April 2015 Dr Cormac Owens

International Randomised Controlled Trial for the Treatment of Newly Diagnosed Ewing’s Sarcoma Family of Tumours

1
Name No. Type Date Opened Principal Investigator(s) Title No. on this trial
AZA-JMML-001 16-50 Collaborative June 2015 Dr Owen Smith

A Phase 2, multicentre, open-label study to evaluate the pharmacokinetics, pharmacodynamics, safety and activity of azacitidine and to compare azacitidine to historical controls in paediatric subjects with newly diagnosed advanced MDS or JMML before HSCT.

1
Name No. Type Date Opened Principal Investigator(s) Title No. on this trial
NBL Registry 16-49 Collaborative April 2015 Dr Cormac Owens

Prospective Study Registry of Peripheral Neuroblastic Tumours Presenting with Spinal Canal Involvement (SCI).

2
Name No. Type Date Opened Principal Investigator(s) Title No. on this trial
EpSSG / NRSTS 2005 16-48 Collaborative October 2012 Dr Jane Pears

A Protocol for Non-Rhabdomyosarcoma Soft Tissue Sarcomas.

4
Name No. Type Date Opened Principal Investigator(s) Title No. on this trial
EpSSG / RMS 2005 16-47 Collaborative October 2011 Dr Cormac Owens

A protocol for non-metastatic rhabdomyosarcoma (incorporates RMS-MET2008: Treatment Arm for Metastatic Disease).

20
Name No. Type Date Opened Principal Investigator(s) Title No. on this trial
EWOG-SAA-2010 16-46 Collaborative April 2012 Dr Owen Smith

Genetic & Immunological Characterisation of Acquire Severe Aplastic Anaemia (SAA) in Children & Adolescents

19
Name No. Type Date Opened Principal Investigator(s) Title No. on this trial
FACT Study 16-45 Collaborative April 2006 Not Applicable

Factors associated with Childhood Tumours StudyFactors associated with Childhood Tumours Study

33
Name No. Type Date Opened Principal Investigator(s) Title No. on this trial
EU-RHAB 16-44 Collaborative October 2012 Dr Michael Capra

European Rhabdoid Registry. A Multinational registry for rhabdoid tumours of any anatomical site

7