About this trial
This study is being done to find out if zanidatamab, when given with chemotherapy plus or minus tislelizumab, is safe and works better than trastuzumab given with chemotherapy.
Advanced human epidermal growth factor 2 (HER2)-positive stomach and esophageal cancers that are no longer treatable with surgery (unresectable) or chemoradiation, and/or have grown or spread to other parts of the body (metastatic)
Where’s this trial being run?
St James’s Hospital
Can I join this study / trial?
The first thing you do is to talk to your doctor and/or the cancer trials research team in your hospital. The contact details for the cancer trials research units in Ireland is here.
Why not Print this page and bring it with you. It will help your doctor and research team advise you.Print this page
For more detailed informationClick Here
Here’s a list of questions you may have for your doctor or local cancer research team.Questions
|Name:||HERIZON-GEA-01 (ZWI-ZW25-301) Zymeworks|
HERIZON-GEA-01 (ZWI-ZW25-301) Zymeworks: A Randomized, Multicenter, Phase 3 Study of Zanidatamab in Combination With Chemotherapy With or Without Tislelizumab in Subjects With HER2-positive Unresectable Locally Advanced or Metastatic Gastroesophageal Adenocarcinoma (GEA)
|Principal Investigator:||Professor Maeve Lowery|
|Global Recruitment Target:||714|
|Ireland Recruitment Target:||6 (competitive)|