LigaSure

Name No. For Patients with Purpose
LigaSure 20-13

breast cancer patients undergoing a mastectomy

To investigate the use of the two cutting and sealing devices currently used in mastectomy, LigaSure™ versus monopolar diathermy. At this time, the device that is utilised is the surgeons own preference.


KEYLYNK-009

Name No. For Patients with Purpose
KEYLYNK-009 19-36

triple negative breast cancer (TNBC)

The purpose of this study is to compare the efficacy of olaparib (MK-7339) plus pembrolizumab (MK-3475) with chemotherapy plus pembrolizumab after induction with first-line chemotherapy plus pembrolizumab in triple negative breast cancer (TNBC).


CA209-7FL

Name No. For Patients with Purpose
CA209-7FL 19-35

high-risk, estrogen receptor-positive, human epidermal growth factor receptor 2-negative (ER+, HER2-) early stage breast cancer

The purpose of this trial is to evaluate the efficacy and safety of nivolumab versus placebo in combination with neoadjuvant (pre-surgery) chemotherapy and adjuvant (post-surgery) endocrine therapy


KEYNOTE-756

Name No. For Patients with Purpose
KEYNOTE-756 18-05 (MK-3475-756)

Newly Diagnosed Breast Cancer

The purpose of this study is to assess the efficacy and safety of pembrolizumab in combination with pre-surgery chemotherapy and post-surgery endocrine therapy in the treatment of adults who have high-risk early-stage ER+/HER2- breast cancer.


ALEXANDRA/IMpassion030

Name No. For Patients with Purpose
ALEXANDRA/IMpassion030 17-15 (WO39391 / BIG 16-05)

Early stage breast cancer

This study will evaluate the efficacy, safety, and pharmacokinetics of adjuvant atezolizumab.


Proteomics / Molecular Breast

Name No. For Patients with Purpose
Proteomics / Molecular Breast 09-07

Breast cancer

The purpose of this trial is to examine the function of different genes and proteins, previously identified to be of interest, and identify new ones, as well as the means by which they interact and differ between cancer cells.