• Breast
Name No. Patient Profile Purpose
Panthera 17-13

Advanced HER2-positive (HER2+) Breast Cancer

The purpose of this trial is to determine the safety and efficacy of the drug copanlisib and the optimum dose when used with trastuzumab emtansine (T-DM1).
  • Breast
Name No. Patient Profile Purpose
NATALEE 18-41 (CLEE011O12301C)

Early Breast Cancer

The purpose of this study is to evaluate efficacy and safety of ribociclib with endocrine therapy as adjuvant treatment in patients with HR+/HER2- Early Breast Cancer.
  • Breast
Name No. Patient Profile Purpose
KEYNOTE-756 18-05 (MK-3475-756)

Newly Diagnosed Breast Cancer

The purpose of this study is to assess the efficacy and safety of pembrolizumab in combination with pre-surgery chemotherapy and post-surgery endocrine therapy in the treatment of adults who have high-risk early-stage ER+/HER2- breast cancer.
  • Breast
Name No. Patient Profile Purpose
ALEXANDRA/IMpassion030 17-15 (WO39391 / BIG 16-05)

Early stage breast cancer

This study will evaluate the efficacy, safety, and pharmacokinetics of adjuvant atezolizumab.
  • Breast
Name No. Patient Profile Purpose
VIOLETTE 17-33 (D5336C 00001)

Metastatic Breast Cancer

To assess the efficacy and safety of agents targeting DNA damage repair.
  • Breast
Name No. Patient Profile Purpose
Recurrence Score 15-34

Estrogen Receptor (ER) positive, lymph node positive early stage breast cancer.

The purpose of this study is to examine the impact of the 21 gene Recurrence Score on chemotherapy recommendations in operable breast cancer in the postoperative and preoperative setting.
  • Breast
Name No. Patient Profile Purpose
NSABP B-51 15-03

Early stage breast cancer.

The purpose of this trial is to compare different radiotherapy treatments for early stage breast cancer patients first treated with chemotherapy and surgery.
  • Breast
Name No. Patient Profile Purpose
PantHER 15-02

HER2+ advanced breast cancer

The purpose of this trial is to determine the safety and efficacy of the drug copanlisib and the optimum dose when used with trastuzumab.
  • Breast
Name No. Patient Profile Purpose
Ovarian Reserve 10-16

Premenopausal breast cancer

This trial investigates the levels of hormones in a patient’s blood, which may predict the likelihood of future infertility.
  • Breast
Name No. Patient Profile Purpose
Proteomics / Molecular Breast 09-07

Breast cancer

The purpose of this trial is to examine the function of different genes and proteins, previously identified to be of interest, and identify new ones, as well as the means by which they interact and differ between cancer cells.