BI Afatinib Trial

Name No. For Patients with Purpose
BI Afatinib Trial CTRIAL-IE 18-23

To determine the maximum tolerated dose (MTD), safety, and efficacy of afatinib monotherapy


SIOP EPENDYMOMA II

Name No. For Patients with Purpose
SIOP EPENDYMOMA II 2013-002766-39

Children, adolescents and young adults with ependymoma

Test


NBL NK Study (TCD)

Name No. For Patients with Purpose
NBL NK Study (TCD)

Neuroblastoma

Targeting metabolism to improve NK cell mediated Immunotherapy for the treatment of Neuroblastoma


LCH IV

Name No. For Patients with Purpose
LCH IV 2011-001699-20

Langerhans cell histiocytosis

International Collaborative Treatment Protocol for Children and Adolescents with LCH.


MONTE Biomarker Study (RCSI)

Name No. For Patients with Purpose
MONTE Biomarker Study (RCSI) 19-04

High Risk Neuroblastoma

Modulation of drug resistance in high risk neurobalstoma through exosomes.


MAPPYACTS

Name No. For Patients with Purpose
MAPPYACTS 18-19

Relapsed or refractory paediatric tumor.

Proof-of-Concept study to stratify targeted therapies adapted to molecular profiling (MAPPYACTS).


ITCC 054

Name No. For Patients with Purpose
ITCC 054 18-24

Paediatric patients with Chronic Myeloid Leukemia.

To establish the efficacy, safety, and tolerability of bosutinib.


PHITT

Name No. For Patients with Purpose
PHITT 18-17

Hepatoblastoma (HB) and Hepatocellular Carcinoma (HCC).

The trial will evaluate whether reducing treatment for low risk Hepatoblastoma (HB) patients maintains their excellent event free survival (EFS) and decreases acute and long-term toxicity.


ITCC 059

Name No. For Patients with Purpose
ITCC 059 18-16

CD22-positive acute lymphocytic leukemia (ALL)


Mye Child

Name No. For Patients with Purpose
Mye Child 16-82

Acute Myeloid Leukemia (AML)

To compare two induction chemotherapy regimens.