DSSG Group: Multiple Myeloma

The target population for this study are patients with relapsed refractory multiple myeloma

This study is a phase 2, randomized, parallel, open-label study to investigate the safety, efficacy, and pharmacokinetics of various dosing regimens of single-agent Belantamab Mafodotin (GSK2857916) in participants with relapsed or refractory multiple myeloma

The target population for this study are patients with relapsed refractory multiple myeloma

This study is a phase 1/2, open-label study to investigate the safety and tolerability, efficacy, pharmacokinetics, and immunogenicity of Modakafusp Alfa (TAK-573) as a single agent in patients with relapsed refractory multiple myeloma

The target population for this study are Mayo Stage IV AL amyloid patients

This study is a Phase III, global, randomised double-blind trial of birtamimab plus standard of care vs placebo plus standard of care in Mayo Stage IV AL amyloid patients

The target population for this study are patients with newly diagnosed multiple myeloma for high dose therapy and autologous stem cell transplant. Patients will have a confirmed diagnosis of multiple myeloma, based on standard IMWG criteria.

This study is a Phase II, multi-centre, single-arm, open-label study to evaluate the efficacy and safety of the combination regimen Isatuximab, Lenalidomide, Bortezomib, and Dexamethasone in patients with newly diagnosed multiple myeloma

The target population for this study are patients with relapsed/refractory multiple myeloma (MM). Patients will have a confirmed diagnosis of MM, with measurable disease as per IMWG criteria, in the second relapse and beyond (third line of therapy and beyond)

This study is a Phase Ib, open label, single arm, adaptive multi-centre clinical study of Cyclophosphamide, Pomalidomide, Dexamethasone and Daratumumab (CPD-DARA) in patients with relapsed/refractory multiple myeloma