Name | No. | For Patients with | Purpose |
---|---|---|---|
MK-3475-630/KEYNOTE-630 | CTRIAL-IE 20-08 | Melanoma |
This is a randomized study that compares pembrolizumab with placebo given as adjuvant therapy in participants with high-risk locally advanced cutaneous squamous cell carcinoma (LA cSCC) that have undergone surgery with curative intent in combination with radiotherapy. The primary hypothesis is that pembrolizumab is superior to placebo in increasing recurrence free survival (RFS). |
DSSG Group: Skin Cancer
R3767-ONC-1613
Name | No. | For Patients with | Purpose |
---|---|---|---|
R3767-ONC-1613 | CTRIAL-IE 20-11 | Melanoma |
This study is to evaluate preliminary anti-tumor activity of REGN3767 alone and in combination with cemiplimab as measured by objective response rate (ORR). |
BMS CA045-001
Name | No. | For Patients with | Purpose |
---|---|---|---|
BMS CA045-001 | CTRIAL-IE 18-51 | Melanoma. |
This study will evaluate the efficacy of NKTR-214 Combined with Nivolumab Versus Nivolumab |
BMS CA209-8FC
Name | No. | For Patients with | Purpose |
---|---|---|---|
BMS CA209-8FC | CTRIAL-IE 19-13 | Melanoma. |
The study will compare the pharmacokinetics of BMSCHO1-Nivolumab Process D to Nivolumab Process C |
CA045-001
Name | No. | For Patients with | Purpose |
---|---|---|---|
CA045-001 | 18-51 | Previously untreated or unresectable or Metastatic Melanoma |
The purpose of the study is to test the effectiveness (how well the drug works), safety, and tolerability of the investigational drug called NKTR-214, when combined with nivolumab versus nivolumab given alone in participants with previously untreated melanoma skin cancer that is either unable to be surgically removed or has spread. |
R2810-ONC-1788
Name | No. | For Patients with | Purpose |
---|---|---|---|
R2810-ONC-1788 | 18-50 | Cutaneous Squamous Cell Carcinoma (High Risk) |
The primary objective of the study is to compare disease-free survival (DFS) of patients with high-risk cutaneous squamous cell carcinoma (CSCC) treated with adjuvant cemiplimab, versus those treated with placebo, after surgery and radiation therapy (RT). |