• Genitourinary
Name No. Patient Profile Purpose
IRONMAN: International Registry for Men with Advanced Prostate Cancer CTRIAL-IE 17-30

Metastatic hormone-sensitive prostate cancer (mHSPC) or castration-resistant prostate cancer (CRPC)

The purpose of this study is to create an international, population-based,
prospective registry of minimum 5,000 men with advanced prostate cancer.
  • Genitourinary
Name No. Patient Profile Purpose
KEYNOTE-564 CTRIAL-IE 18-31

Renal cell carcinoma (kidney cancer) post nephrectomy

The purpose of this trial is to evaluate the efficacy and safety of pembrolizumab in the adjuvant treatment of RCC post nephrectomy.
  • Genitourinary
Name No. Patient Profile Purpose
PEACE III CTRIAL-IE 16-21

asymptomatic or mildly symptomatic castration resistant prostate cancer patients metastatic to bone

The purpose of this study is to find out whether the combination of Xofigo® (radium-223) and Xtandi® (enzalutamide) shows better activity against Xtandi® alone (enzalutamide) in metastatic prostate cancer and if the combination of Xofigo® (radium-223) and Xtandi® (enzalutamide) is safe.
  • Genitourinary
Name No. Patient Profile Purpose
DICE Study CTRIAL-IE 17-17

Progressive Metastatic Resistant Prostate Cancer and bone metastases

The purpose of this study is to investigate the radiographic progression free survival of patients treated with Denosumab in combination with Enzalutamide in progressive metastatic castrate resistent prostate cancer.
  • Genitourinary
Name No. Patient Profile Purpose
NRG GU005 CTRIAL-IE 18-02

Localised intermediate risk prostate cancer

To determine if stereotactic body radiation therapy (SBRT) is superior to hypofractionated intensity modulated radiation therapy (IMRT) in the treatment of localised intermediate risk prostate cancer.
  • Genitourinary
Name No. Patient Profile Purpose
17403/ FORT-1 17-04

FGFR (Fibroblast Growth Factor Receptor)-Positive Locally Advanced or Metastatic Urothelial Carcinoma (cancer that typically occurs in the urinary system).

The purpose of this trial is to evaluate the efficacy and safety of rogaratinib (BAY 1163877) compared to chemotherapy.
  • Genitourinary
Name No. Patient Profile Purpose
E7080-G000-307 16-69

Advanced/metastatic renal cell carcinoma (kidney cancer).

The purpose of this trial is to assess the safety and efficacy of the drug lenvatinib in combination with everolimus or pembrolizumab versus sunitinib alone in first-line treatment of participants with advanced renal cell carcinoma.
  • Genitourinary
Name No. Patient Profile Purpose
CA209-274 16-70

Cancer originating in the bladder, ureter or renal pelvis

The purpose of this trial is to determine if the drug nivolumab versus placebo prevents cancer recurrence in participants with bladder or upper urinary tract cancer, following surgery to remove the cancer.
  • Genitourinary
Name No. Patient Profile Purpose
IPCOR 16-07

Prostate cancer

The main objective is to collect detailed clinical and quality of life data on Irish men’s prostate cancer journey.
  • Genitourinary
Name No. Patient Profile Purpose
Neo-adjuvant abiraterone prostate study 13-23

Prostate cancer.

The purpose of this trial is to focus on the potential role of the drug abiraterone acetate.