AFG Post-RT

About this trial

This study is for women who have been treated with radiotherapy for cancer of the vulva. Women who have undergone local radiotherapy to treat cancer of the vulva can experience both acute (short-term) and chronic (medium to long-term) side effects. These side effects include discomfort, pain, itching, dryness and changes to the quality and appearance of their skin. These symptoms vary in severity and, for some women, can be difficult to treat.

The purpose of this study is to trial a new treatment for these symptoms. Autologous fat grafting (or lipo-transfer) is a procedure that involves taking fat from a part of the body that is rich in fat (such as the flank for the buttocks region) and injecting part of this fat under the skin of the vulva.

There is evidence that autologous fat grafting can have regenerative and immunomodulatory effects. Through this study, we hope to find out whether autologous fat grafting can improve some of the chronic vulval side effects that women may experience following radiotherapy for vulval cancer.

Patient Profile

• History of vulval cancer
• History of vulval radiotherapy
• Remission x 12 months

Where’s this trial being run?

Mater Misericordiae University Hospital

Can I join this study / trial?

The first thing you do is to talk to your doctor and/or the cancer trials research team in your hospital. The contact details for the cancer trials research units in Ireland is here.

Why not Print this page and bring it with you. It will help your doctor and research team advise you.

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For more detailed information

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Questions?

Here’s a list of questions you may have for your doctor or local cancer research team.

Questions

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Summary Data

Name:	AFG Post-RT
Number:	24-117
Full Title:	AFG Post-RT / Autologous fat grafting for vulval pain and atrophy after cancer: A pilot study to examine the feasibility, safety and effect of autologous fat grafting (AFG) in the treatment of chronic vulval symptoms following radiotherapy.

Principal Investigator:	Prof. Donal Brennan (with Dr. Aisling McDonnell)
Type:
Sponsor:	Mater Hospital
Recruitment Started:	Global: Ireland: July 2024

Global Recruitment Target:
Ireland Recruitment Target:	5