About this trial

Complete resection at secondary cytoreductive surgery is associated with prolonged progression free and overall survival for patients with relapsed ovarian cancer. Secondary cytoreductive surgery has no impact on survival rates, if macroscopically tumor clearance cannot be achieved. Therefore, in order to avoid unnecessary perioperative morbidity and mortality, selection of patients who will undergo secondary tumor debulking is crucial. This study aims to improve upon the contemporary Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) score by including additional clinical variables like circulating HE4 and CA125 levels to predict surgical outcome at secondary cytoreduction.

Patient Profile

Where’s this trial being run?

Beacon Hospital

Can I join this study / trial?

The first thing you do is to talk to your doctor and/or the cancer trials research team in your hospital. The contact details for the cancer trials research units in Ireland is here.

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For more detailed information


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Summary Data

Number: 22-05
Full Title:

Prospective Study of HE4 serum Level in Patients with First Relapsed Ovarian

Principal Investigator: Dr. Sharon O'Toole
Type: Collaborative


Recruitment Started: Global:
Global Recruitment Target:
Ireland Recruitment Target: