PRESERVE

About this trial

This is a randomized phase II study. Patients will be randomised between current standard of care treatment (Arm 1) vs. omission of radiation to the pathologically node negative dissected hemi-neck(s) (Arm 2) in a 1:2 ratio.

Patient Profile

For patients with resected oral cavity squamous cell carcinoma with an indication for post-operative radiation therapy, and at least one pathologically node negative dissected hemi-neck.

Where’s this trial being run?

St Luke’s Radiation Oncology Network @ St Luke’s Hospital

Can I join this study / trial?

The first thing you do is to talk to your doctor and/or the cancer trials research team in your hospital. The contact details for the cancer trials research units in Ireland is here.

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For more detailed information

Questions?

Here’s a list of questions you may have for your doctor or local cancer research team.


Summary Data

Name: PRESERVE
Number: 20-04
Full Title:

Preservation of Swallowing in Resected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial

Principal Investigator: Dr Sinéad Brennan
Type: Collaborative
Sponsor:

Dr David Palma, Lawson Health Research Institute

Recruitment Started: Global: December 2019
Ireland: March 2022
Global Recruitment Target: 90
Ireland Recruitment Target: 24