About this trial
This is a randomized phase II study. Patients will be randomised between current standard of care treatment (Arm 1) vs. omission of radiation to the pathologically node negative dissected hemi-neck(s) (Arm 2) in a 1:2 ratio.
Patient Profile
For patients with resected oral cavity squamous cell carcinoma with an indication for post-operative radiation therapy, and at least one pathologically node negative dissected hemi-neck.
Where’s this trial being run?
Cork University Hospital, St Luke’s Radiation Oncology Network @ Beaumont Hospital, St Luke’s Radiation Oncology Network @ St Luke’s Hospital, and University Hospital Galway
Can I join this study / trial?
The first thing you do is to talk to your doctor and/or the cancer trials research team in your hospital. The contact details for the cancer trials research units in Ireland is here.
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QuestionsSummary Data
| Name: | PRESERVE |
|---|---|
| Number: | 20-04 |
| Full Title: | Preservation of Swallowing in Resected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial |
| Principal Investigator: | Dr Sinéad Brennan |
|---|---|
| Type: | Collaborative |
| Sponsor: | Dr David Palma, Lawson Health Research Institute |
| Recruitment Started: |
Global: December 2019 Ireland: March 2022 |
| Global Recruitment Target: | 90 |
|---|---|
| Ireland Recruitment Target: | 24 |