About this trial

“The PHITT trial is an over-arching study for patients with Hepatoblastoma (HB) and Hepatocellular Carcinoma (HCC). This trial will use a risk-adapted approach to the treatment of children diagnosed with HB. Children with HCC will be included as a separate cohort.

The trial will evaluate whether reducing treatment for low risk HB patients maintains their excellent event free survival (EFS) and decreases acute and long-term toxicity. Intensification of therapy with the use of novel agents will be evaluated in the high risk group. The trial will also compare three different regimens in intermediate risk HB.”

Patient Profile

Clinical diagnosis of Hepatoblastoma (HB) and histologically defined diagnosis of HB or Hepatocellular Cancer (HCC).

Where’s this trial being run?

Crumlin Children’s Hospital

Can I join this study / trial?

The first thing you do is to talk to your doctor and/or the cancer trials research team in your hospital. The contact details for the cancer trials research units in Ireland is here.

Why not Print this page and bring it with you. It will help your doctor and research team advise you.

For more detailed information


Here’s a list of questions you may have for your doctor or local cancer research team.

Summary Data

Number: 18-17
Full Title:

Paediatric Hepatic International Tumour Trial.

Principal Investigator: Michael Capra
Type: Collaborative

University of Birmingham

Recruitment Started: Global: August 2017
Ireland: 2018
Global Recruitment Target: 300
Ireland Recruitment Target: Not Available